Understanding Treatment Duration
Why Ibogaine Requires More Than a Weekend
Ibogaine is not a single-dose intervention delivered in an afternoon. The compound initiates a cascade of neurochemical changes. mu-opioid receptor modulation, serotonin transporter binding, GDNF upregulation. that unfold across days and weeks. Attempting to compress this process into a 48-hour turnaround ignores the pharmacokinetics of ibogaine and its metabolite noribogaine, which has a half-life of approximately 28 hours and continues supporting receptor function long after the primary experience resolves.
The neuroplasticity window opened by ibogaine is one of the most therapeutically valuable aspects of treatment. During this window, the brain demonstrates heightened capacity for new pattern formation, emotional processing, and behavioral change. Anchoring this window with structured integration work. psychological sessions, somatic processing, nutritional support, and community. requires on-site time that cannot be eliminated without compromising the outcome.
Rushed ibogaine treatment is a false economy. Facilities that discharge patients within 24 hours of the flood dose forgo the early integration phase that converts a profound neurochemical experience into lasting behavioral change. MindScape's 7 to 14 day programs are calibrated to the actual pharmacology and psychology of ibogaine recovery, not to what is operationally convenient for a high-volume clinic.
Treatment Programs
Duration by Program Type
5-Day Ibogaine Retreat: $7,500
A focused ibogaine retreat for individuals without active substance dependency or antidepressant use. Designed for personal growth, neuroplasticity enhancement, and deep introspective work. Includes full medical supervision, wellness activities, and 90-day integration support.
7-Day Microdose Program: $8,500
Designed for conditions that respond to sub-perceptual ibogaine dosing, including mood disorders, cognitive concerns, and personal development. A structured microdose series is administered across 5 to 6 days with daily integration sessions and comprehensive wellness support. Suitable for patients without opioid or heavy alcohol dependency.
10-Day Alcohol Program: $11,500
Alcohol dependency requires a carefully sequenced protocol that begins with TA booster sessions before the flood dose. The 10-day program accommodates proper pre-loading, the primary ibogaine session, initial recovery, and structured integration before departure. Patients complete an alcohol taper during the pre-arrival preparation window.
10-14 Day Opioid Program: $13,500
Opioid dependency is treated with MindScape's TA booster pre-loading protocol, which initiates progressive noribogaine accumulation and mu-opioid receptor modulation before the HCl flood dose. This sequencing requires 10 to 14 days on-site. Methadone and Suboxone patients complete a preparatory taper or bridge protocol before arriving.
14-Day Parkinson's / Extended Program: $15,500
Neurological conditions including Parkinson's disease require extended on-site time to allow for cumulative GDNF upregulation through a twice-daily TA booster sequence across multiple days before the flood session. The 14-day program also incorporates daily physiotherapy, movement therapy, and structured neurological monitoring throughout.
Day-by-Day Timeline
Your Treatment Journey
Week Before Arrival: Screening & Selective Pre-Arrival Steps
The preparation window spans 2 to 6 weeks before your arrival date depending on your substances and current medications. All patients complete a 12-lead EKG, comprehensive bloodwork, and a detailed medical intake with our clinical team. Patients on methadone or buprenorphine complete a structured pre-arrival transition. MAOIs, tricyclic antidepressants, lithium, tramadol, and Class III antiarrhythmics must be cleared before arrival. SSRIs, SNRIs, benzodiazepines, and Z-drugs do NOT require an at-home taper. Patients arrive on their current prescribed dose and the taper is performed onsite under continuous physician supervision and telemetry, with twice-daily ibogaine TA (total alkaloid) booster doses bridging serotonergic and GABAergic tone during washout. This phase is where treatment safety is established.
Days 1-2: Arrival, Assessment & Medical Stabilization
You arrive at MindScape Retreat on Cozumel Island, where a final medical evaluation is completed before treatment begins. Repeat cardiac screening, hydration assessment, and a clinical interview with our medical director finalize your ibogaine protocol. You settle into your private accommodation, meet the care team, and acclimate to the retreat environment. No treatment is rushed. The first two days are dedicated to ensuring you are medically stable and emotionally prepared.
Days 3-7: TA Boosters & Microdose Sessions
For opioid and alcohol programs, ibogaine TA booster doses are administered across several consecutive days. Each session lasts 4 to 6 hours and systematically builds noribogaine plasma levels, initiates mu-opioid receptor modulation, and begins the GDNF upregulation sequence. Patients in the 7-day microdose program receive their full series during this phase. All sessions are conducted with continuous cardiac monitoring and physician supervision.
Days 7-10: Flood Dose, Initial Recovery & Integration
The primary ibogaine HCl flood dose is administered in a medically controlled setting. The experience lasts 12 to 24 hours, with the peak visionary and introspective phase running 8 to 12 hours. Physicians and nurses monitor vital signs, cardiac rhythm, and neurological response continuously. Following resolution of the acute experience, patients enter deep rest. Initial integration sessions with our psychologists begin before discharge, while the neuroplastic window is fully open.
Days 10-14: Integration, Wellness Work & Departure
The final days of your on-site program are dedicated to consolidating the shifts initiated during treatment. Daily sessions with our clinical psychologists, yoga and movement therapy, nutritional support, and somatic processing help anchor the insights and neurochemical changes of the treatment experience. Your personalized 90-day integration plan is finalized with scheduled coaching calls, community access, and coordination with your home physician before departure.
The 90-Day Window
Why Integration Is Part of Treatment Duration
Noribogaine, ibogaine's primary active metabolite, does not disappear when you leave Cozumel. It remains pharmacologically active in the body for weeks to months following treatment, continuing to modulate serotonin transporters and support emotional stability. The full neuroplastic window opened by ibogaine extends approximately 3 to 6 months post-treatment. This is not an afterthought. it is a pharmacological reality that defines the true duration of ibogaine therapy.
MindScape's 90-day integration framework is built around this window. Structured coaching calls at 2, 4, 6, 8, and 12 weeks post-discharge are timed to meet patients at key points in the integration arc. Private patient community access provides peer support from others in the same post-treatment window. Psychologist availability for unscheduled support ensures that difficult integration periods do not go unaddressed.
Long-term outcome research on ibogaine consistently shows that patients who engage meaningfully with structured aftercare during the 90-day post-treatment window achieve substantially better sustained sobriety and psychological outcomes than those who complete the on-site program alone. Integration is not supplementary care. it is the phase where the neurochemical opening created by ibogaine is translated into permanent change.
Our Commitment
We Will Never Rush You Out the Door
There is an uncomfortable economic truth about residential treatment: the fastest way to make a clinic more profitable is to shorten every stay and turn the rooms over faster. We could run that model. We refuse to, because our goal is not to get you in and out. It is for your treatment to succeed. We size our treatment programs to what recovery actually requires: unhurried preparation, the treatment itself, and the first days of integration while the neuroplastic window is open.
We hold this line because we see what the opposite produces. Many of the people who arrive in Cozumel have been through treatment somewhere else before, and what they describe is remarkably consistent: a program that ran on a schedule, a discharge as soon as the acute phase passed, and the hardest part of recovery left to happen alone at home. In our clinical experience, when treatment does not hold, the most common reason is not the medicine. It is a process that was cut short.
So our commitment is simple: we will never rush you out the door. Discharge is a clinical decision our medical team makes with you, never a turnover decision made around you. If you need more time to stabilize, to process, or simply to feel ready, that starts as a conversation with your physician, and if it means extending your stay, admissions confirms exactly what that costs with you before anything changes. We would rather treat fewer people properly than more people quickly.
Duration Questions
Treatment Duration, Frequently Asked Questions
Program Investment
Transparent, All-Inclusive Pricing
5-Day Ibogaine Retreat
$7,500
5-day wellness and neuroplasticity ibogaine retreat. All-inclusive.
5-MeO-DMT (Bufo) Day Session
from $1,450
Single-day guided 5-MeO-DMT session: $1,450 at Casa Selva or The Hacienda, $2,200 private at the Oceanfront Residence.
Ibogaine Protocol
$13,500
10 to 14 day all-inclusive program. Full opioid detox and neurochemical reset.
All pricing includes accommodations, meals, medical supervision, pre-treatment preparation, NAD+ infusions, and 90-day integration support. Programs of 10 days or longer include a one-month aftercare microdose supply at discharge. No hidden fees.
Related Treatment Resources
Every MindScape treatment program includes a guided 5-MeO-DMT (Bufo) ceremony, part of the all-inclusive price, not an add-on.
Precision dosing
Your main dose is measured, not estimated
Before the main session, we give a short series of low, sub-psychoactive ibogaine TA boosters. Each one is a measurement. Ibogaine and its long-lived metabolite noribogaine both affect the heart's hERG potassium channel, and that effect is dose-dependent, so instead of predicting how you will respond we observe it directly at doses far below a full session. Your main dose is then chosen from your own cardiac response and the margin you have left.
No ibogaine given. 12-lead ECG, electrolytes and liver panel establish the starting point. A baseline outside safe limits stops the programme here.
These are the measurements the protocol is built around. The trace above is a schematic used to explain the method; it is not a recording of a patient, and the values shown are illustrative rather than results.
How the booster protocol works →