The iboga plant, in one paragraph
Tabernanthe iboga Baill. is an evergreen shrub in the dogbane family, Apocynaceae, native to the rainforest understorey of Central Africa. Its root bark contains roughly five to six percent total indole alkaloids, about eighty percent of which is ibogaine, alongside ibogaline, ibogamine, tabernanthine and a dozen or so relatives. The plant is central to the Bwiti spiritual tradition of Gabon, where it has been treated as national patrimony since 2000 and, since a decree of 22 May 2026, as national strategic heritage requiring government authorisation for almost any use. Iboga is the plant. Ibogaine is one compound taken out of it. The two words are not interchangeable, and the difference matters for dosing, for legality and for conservation.
- Botanical name: Tabernanthe iboga Baill., family Apocynaceae, 2n = 22
- Native range: Cameroon east to eastern DR Congo, south to central Angola, centred on Gabon
- Habit: evergreen understorey shrub to about 4 m, trunk to roughly 10 cm across
- Alkaloid-bearing part: root bark, about 5 to 6 percent total indole alkaloids
- Common names: iboga, eboka, bois sacre (sacred wood), bois amer (bitter wood)
Botany
A slow understorey shrub, not a tree and not a vine
Tabernanthe iboga belongs to the Apocynaceae, the dogbane family, which also gives us periwinkle and oleander and a great many alkaloid-rich species. It grows as an evergreen shrub of the forest understorey, reaching about four metres with dichotomous branching and a trunk up to roughly ten centimetres in diameter. Leaves sit in opposite pairs, narrowly elliptical to obovate, anywhere from two and a half to twenty-two centimetres long depending on the plant and its position in the canopy shade.
The flowers are easy to miss. They are small, fragrant, five-parted, white or cream with red to purple markings. The fruit is more conspicuous: a globose to ovoid berry three to six and a half centimetres long that ripens yellow to red and holds many seeds. The pulp is sweet and is not where the alkaloids are, which is worth saying plainly because photographs of the fruit often circulate with claims attached to them that belong to the root.
Its habitat is forest understorey, riverine and swamp forest, and wet savanna, from sea level to about 1,500 metres. The natural range runs from Cameroon east into eastern Democratic Republic of the Congo and south to central Angola, taking in Gabon, the Republic of the Congo and Equatorial Guinea along the way. It has been brought into cultivation in parts of West Africa including Cote d'Ivoire. It grows nowhere wild in the Americas, which is one reason nearly every conversation about supply eventually comes back to Gabon.
Propagation is by fresh seed or by cuttings. Scarification improves germination and seedlings need shading, while cuttings root readily in humid soil and can flower within about four months. Those figures come from the Plant Resources of Tropical Africa monograph, which remains the most careful published description of the species.
Where the alkaloids sit
Almost everything is in the root bark, and that is the problem
Alkaloid content is not spread evenly through the plant. Root bark carries roughly five to six percent total indole alkaloids, and about eighty percent of that fraction is ibogaine. Whole roots run lower, around one to two and a half percent. Stem bark is near two percent, seeds about one percent, and the leaves between 0.4 and 0.8 percent with no ibogaine in them at all.
That distribution explains a lot. It explains why traditional preparation scrapes root bark rather than picking leaves. It explains why the plant is usually damaged or killed to harvest it, unlike a tree whose stem bark can be taken and left to regrow. And it explains why anyone selling you iboga leaf as an equivalent product is either confused or not being straight with you.
It also explains why supervised programmes do not dose raw bark. The alkaloid fraction varies with the individual plant, its age and its growing conditions, so a gram of one plant's bark is not clinically the same as a gram of another's. Clinical work therefore uses either purified ibogaine hydrochloride, a single compound at a known concentration, or a standardised total alkaloid extract. Those two are not interchangeable either, and we explain the difference at length in TA versus HCl.
Ibogaine is the most abundant alkaloid but not the only active one. Ibogaline, ibogamine, tabernanthine and iboluteine appear alongside it, and ibogaine itself is metabolised in the body into noribogaine, which lasts far longer than the parent compound. Our iboga alkaloid encyclopedia has a profile for each one, including formula, receptor activity and citations.
From plant to preparation
The forms you will actually encounter
Bwiti
The plant belongs to a living tradition, not to us
Iboga root bark is central to Bwiti, a spiritual tradition practised in Gabon and neighbouring countries, above all in initiation. This is a living religion with initiated practitioners today, not an anthropological footnote, and Gabonese communities regard both the plant and the knowledge attached to it as their inheritance. Root bark has also had more everyday uses, taken as a tonic against fatigue and used in various local medicinal preparations.
That history is also how the compound reached Western medicine, and the route is worth being honest about. Ibogaine's effect on opioid dependence was not predicted in a laboratory. It was noticed in 1962 by Howard Lotsof, who took iboga for other reasons and found his heroin withdrawal did not arrive. Everything that has happened since, including the clinical programmes and the patents and the state research funding, follows from knowledge that Central African communities held first.
We run a medical programme in Mexico. It is not a Bwiti ceremony and we do not present it as one, because dressing clinical care in someone else's religious language would be both inaccurate and disrespectful. We think the useful thing a clinic can do is say clearly where the medicine comes from, source it in ways that do not deepen the pressure on wild populations, and not pretend the tradition is ours.
Timeline
From forest plant to regulated strategic resource
1901 — first isolation
Ibogaine is isolated from Tabernanthe iboga root bark, independently by Dybowski and Landrin and by Haller and Heckel in the same year, working from Gabonese material.
1930s to 1966 — sold in France
Purified ibogaine is marketed in France in 8 mg tablets under the name Lambarene, as a stimulant and tonic. It is withdrawn from the French market in 1966.
1962 — the addiction observation
Howard Lotsof reports that a single dose interrupted his heroin dependence. He is later granted US Patent 4,499,096 in 1985, and rodent work by Dzoljic and colleagues in 1988 confirms attenuation of opioid withdrawal signs.
2000 — national patrimony
Gabon formally recognises iboga as national patrimony, acknowledging the plant and the Bwiti tradition around it as cultural heritage.
2019 — exports banned
Gabon prohibits iboga exports pending compliance with the Nagoya Protocol, the international agreement on access to genetic resources and fair sharing of the benefits arising from their use.
22 May 2026 — strategic heritage
A Gabonese decree classifies iboga and its derivatives as national strategic heritage. Access, harvesting, research, transformation, commercialisation and activity abroad involving the plant or its associated traditional knowledge all require prior authorisation from the ministry responsible for culture, granted only on the binding opinion of a new interministerial technical commission.
Conservation
Least Concern on paper, under real pressure in the forest
The IUCN Red List records Tabernanthe iboga as Least Concern, citing a wide distribution. That assessment rests on limited field data, and conservation organisations working on iboga have questioned whether it reflects what is actually happening on the ground. It is worth knowing the official status and worth not stopping there.
The concrete concerns are documented. The Plant Resources of Tropical Africa monograph notes that no germplasm collections of the species exist and that large quantities are harvested from the wild, which puts genetic diversity at risk. Because the alkaloids are concentrated in root bark, harvesting generally damages or destroys the individual plant. Rising international interest in ibogaine has pushed prices up sharply inside Gabon, and higher prices on a wild-harvested root are exactly the conditions under which poaching pressure increases. Gabon's 2026 decree is best understood in that light: a sovereignty and stewardship measure, not merely a trade restriction.
There is a real technical answer to some of this. Ibogaine can be produced semi-synthetically from voacangine, an iboga-type alkaloid present at higher yield in the root bark of Voacanga africana, a faster-growing related tree whose bark can be taken without killing it. An optimised procedure for obtaining voacangine from Voacanga africana root bark was published in ACS Omega in 2021 for precisely this reason, and total synthesis routes are being developed as well. The ibogaine hydrochloride used in clinical settings, including ours, is commonly semi-synthesised by this route rather than extracted from wild iboga.
None of that makes sourcing a solved problem, and we would rather say so than claim otherwise. The practical test for any provider is simple: ask which route their material came from and whether they can say. A supplier who cannot answer that question is telling you something. We wrote more about the wider picture in our piece on the iboga conservation crisis.
Measured & safe
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Common questions
The iboga plant, answered directly
Primary References
Our protocols align with the primary scientific literature, including the MAPS Ibogaine Investigator's Brochure (July 2026), NIDA's psychedelic & dissociative drugs research, and registered trials on ClinicalTrials.gov, Tabernanthe iboga monograph, Plant Resources of Tropical Africa (PROTA) — botany, alkaloid distribution, propagation, conservation, Tabernanthe iboga Baill., Plants of the World Online, Royal Botanic Gardens Kew — accepted name and native distribution, Efficient Access to the Iboga Skeleton: Optimized Procedure to Obtain Voacangine from Voacanga africana Root Bark (ACS Omega, 2021), Iboga conservation overview, Chacruna Institute — IUCN status and the limits of the available field data. Ibogaine remains investigational; we pair published evidence with measured, real-world outcome tracking.
Go deeper: what ibogaine is · the iboga alkaloid encyclopedia · TA versus HCl · how ibogaine works in the brain · legal status by country · side effects and contraindications · the full treatment guide
