MindScape Retreat Ibogaine Treatment Clinic in Cozumel Mexico
MindScape Retreat
Ibogaine Treatment Center. Cozumel, Mexico

The World's Most Comprehensive
Ibogaine Treatment Clinic

A luxurious, all-inclusive retreat combining Ibogaine HCL, Ibogaine TA, 5-MeO-DMT, and NAD+ infusions. the only center on earth to use this synergistic protocol.

Begin Your Screening
900+
Patients Treated
Across addiction, PTSD & depression
7+
Day All-Inclusive Program
Starting at $7,500 USD
3
Synergistic Medicines
Ibogaine + 5-MeO-DMT + NAD+
12
Natural Alkaloids (TA)
Full-spectrum Iboga root extract
DA
Medically reviewed by Dr Arellano, M.D.
Clinical Director, MindScape Retreat · Board-certified physician specializing in ibogaine-assisted detoxification with over 900 patients treated.
Last reviewed: March 2026

How Ibogaine Works

The Clay Metaphor: Resetting the Brain at Its Core

Envision the brain as a rigid, unyielding block of clay. an apt metaphor for our ingrained thought patterns and habitual behaviors. Years of conditioning have made it hard and brittle, symbolizing the difficulty of changing long-established ways of thinking and acting.

Traditional therapy works like a sculptor meticulously chipping away: slow, painstaking, often spanning years with a relatively low success rate. An ibogaine treatment is like warming up the clay. effectively resetting the clock on your brain. The neural architecture becomes malleable and adaptable in a considerably shorter timeframe.

As the clay softens, new neural connections form rapidly. Our therapists work in this window of heightened neuroplasticity, guiding the reshaping of entrenched patterns. The result is an awakened, rejuvenated brain. ready to build new, enduring ones.

Our Unique Protocol

The Only Center Using Both Ibogaine HCL and Ibogaine TA Extract

Most ibogaine clinics use only one form of the medicine. MindScape is the only treatment center in the world to administer both Ibogaine HCL. highly pure for precise dosing. and Ibogaine Total Alkaloid (TA) extract in a single, synergistic protocol.

Ibogaine TA retains all 12 natural alkaloids found in the Tabernanthe iboga root, delivering neuroprotective, anti-inflammatory, and emotionally restorative benefits that pure HCL alone cannot fully replicate. Together, they create the most complete neural reset available.

We further amplify this with 5-MeO-DMT's deep spiritual insights and NAD+ cellular restoration. It is not just about the experience. it is the structured therapeutic framework surrounding three synergistic medicines that unlocks truly lasting transformation.

What Is Ibogaine Treatment?

Ibogaine is a naturally occurring psychoactive alkaloid from the Tabernanthe iboga plant that resets addiction, depression, and trauma at the neurochemical level. It eliminates withdrawal symptoms in hours, restores receptor sensitivity, and opens a window of neuroplasticity for lasting behavioral change.

  • Eliminates opioid withdrawal in 12–24 hours
  • Upregulates GDNF and BDNF for neural repair
  • Addresses addiction, PTSD, depression, and TBI simultaneously
  • 900+ patients treated with documented clinical outcomes

Why MindScape

MindScape vs Other Ibogaine Clinics

 IbogaineTypical Ibogaine Clinic
ProtocolHCL + TA extract + 5-MeO-DMT + NAD+Single form (HCL or TA only)
Medical Staff24/7 physician + nursing supervisionNurse or sitter on-call
Cardiac ScreeningEKG, bloodwork, liver panel requiredVaries — sometimes optional
Integration90-day post-retreat support includedLimited or no aftercare
Accommodation5-star private rooms, all-inclusiveShared rooms, meals extra
Conditions Treated12+ conditions with specialized protocolsPrimarily addiction only

Patient safety is the foundation of our protocol. Learn about our comprehensive cardiac screening and safety protocols, including EKG evaluation, liver panels, and contraindication management. Review our documented outcomes across 900+ patients treated since 2019.

Areas of Specialization

Ibogaine Therapy for a Wide Range of Conditions

Opioid Addiction

Ibogaine interrupts opioid dependency at the receptor level, eliminating withdrawal symptoms and cravings. Effective for fentanyl, heroin, prescription opioids, and kratom.

Kratom Addiction

Kratom dependency is uniquely difficult to break due to its opioid-like binding profile. Ibogaine resets the mu-opioid receptors responsible, eliminating withdrawal without prolonged suffering.

Methadone & Suboxone

One of the most demanding detoxifications in medicine. Our protocol safely bridges patients off methadone and Suboxone with precision medical care throughout.

Alcohol & Cocaine

Targets the root compulsive behaviors beneath alcohol and cocaine addiction, eliminating cravings and withdrawal while addressing underlying trauma and emotional dysregulation.

Depression

Tailored for treatment-resistant depression. Experience a profound reset of the serotonin and dopamine systems that antidepressants alone cannot achieve.

PTSD, CPTSD & TBI

Our scientific approach fosters neurochemical balance and supports long-term recovery from trauma. Ibogaine facilitates rapid processing of traumatic memory without re-traumatization.

SSRI Discontinuation

A supervised 10 to 14 day protocol to safely taper off antidepressants, reset the serotonin system, and achieve lasting emotional freedom from long-term SSRI dependence.

Parkinson's Disease

A 14 to 18 day microdosing protocol promoting neuroregeneration, enhanced dopamine pathways, and alleviation of tremors and rigidity under daily medical supervision.

Anxiety

Ibogaine offers a holistic reset of dysregulated fear and stress circuits. Our integrative approach combines medicine work with evidence-based therapies for lasting relief.

Multiple Sclerosis

Ibogaine's GDNF upregulation and anti-inflammatory properties offer a neuroprotective pathway for MS patients seeking symptom relief and neurological support.

5-MeO-DMT

Bufo alvarius 5-MeO-DMT facilitates one of the most profound non-dual states available to human consciousness, offering rapid dissolution of ego-identification and lasting insight.

Psilocybin Therapy

Our psilocybin retreat program combines ceremonial and therapeutic frameworks to support deep emotional healing, spiritual expansion, and sustainable personal transformation.

Your Journey. 4 Steps

What to Expect on Your Ibogaine Therapy Journey

01

Pre-Screening & Application

Our professional, no-obligation screening process ensures ibogaine-assisted therapy is the right fit. We conduct thorough medical history review, cardiac evaluation (EKG), bloodwork, and psychological assessment. After completing screening, a deposit secures your selected retreat dates.

02

Pre-Retreat Preparation

Prior to arrival, you engage in two preparation sessions with a qualified psychologist. These ensure you are mentally and physically ready. You receive detailed pre-treatment protocols including dietary guidelines, medication adjustments, and intention-setting frameworks.

03

Ibogaine-Assisted Therapy in Cozumel

A comprehensive 7+ day all-inclusive stay at our luxury Cozumel accommodation. Nutritious wellness meals, guided workshops, mindfulness practices, snorkel tours, daily excursions, and beach breaks are woven into a structured therapeutic program alongside medically supervised ibogaine treatment.

04

Post-Retreat Integration Therapy

The medicine opens the door, and integration therapy keeps it open. Up to six months post-retreat, you continue to receive dedicated psychologist support ensuring the lasting impact of your transformation, including structured integration calls and community connection.

All-Inclusive Program

Everything Included in Your Stay

5-star accommodation with private room and full en-suite bathroom
All nutritious meals crafted for optimal healing and wellness
Daily meditation, yoga, and mindfulness exercises
Sound therapy with singing bowls
Cold Water Immersion Therapy (Ice Bath Therapy)
Temescal (traditional Mayan Sauna)
1-on-1 individual therapy sessions
Group therapy sessions
1 to 3 Ibogaine treatment sessions (HCL + TA full-spectrum protocol)
Optional 5-MeO-DMT therapy session included
NAD+ infusion therapy
Therapeutic massage
Snorkel & El Cielo Tour
Shore excursions and island adventures
Beach breaks and nature immersion activities
Two pre-retreat preparation sessions with psychologist
Up to 90 days of post-retreat integration support
Continuous physician and nursing supervision throughout
From $7,500

7-day core program starting price. Specialized programs: Parkinson's (14 to 18 day), SSRI Discontinuation (10 to 14 day), Opioid (10 to 12 day), and Alcohol (14-day) are individually priced. Contact us for a personalized assessment and exact program quote.

Investment in Your Healing

Program Pricing

Core Program. 7 Day

$7,500

Addiction, PTSD, depression, anxiety, trauma, personal growth & reset. Full all-inclusive stay.

SSRI / Opioid. 10 to 14 Day

$12,500

SSRI discontinuation or opioid addiction. Extended medical supervision and tapering protocol.

Parkinson's. 14-18 Day

$14,500

Neuroregeneration microdosing program. Dopamine pathway support with daily physician monitoring.

All programs include the full all-inclusive package above. Pricing varies by program length and individual medical needs. Payment plans available upon request. Contact us for a no-obligation consultation and personalized quote.

Clinical FAQs

Questions About Our Clinical Protocol

We are the only center in the world to administer both Ibogaine HCL and Ibogaine Total Alkaloid (TA) extract in a single protocol. We further combine this with 5-MeO-DMT and NAD+ infusions. Our program is fully all-inclusive with 5-star accommodation, a multi-disciplinary team of physicians, psychologists, and wellness specialists, and up to 90 days of post-retreat integration support.

A board-certified physician and trained nurse remain at your bedside throughout the entire session, typically 12 to 24 hours. Continuous cardiac monitoring via telemetry, pulse oximetry, and blood pressure checks occur at regular intervals. IV hydration and supplemental oxygen are available immediately if needed. Our monitoring protocol meets or exceeds published clinical safety guidelines for ibogaine administration.

Ibogaine HCL is pharmaceutical-grade and allows precise dosing for the primary neurological reset. Ibogaine TA retains all 12 natural alkaloids from the iboga root, delivering neuroprotective, anti-inflammatory, and emotionally restorative effects that pure HCL alone cannot replicate. Administering both in sequence produces a more complete and sustained neural restructuring than either form alone.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme critical to cellular energy production and DNA repair. After ibogaine opens the window of neuroplasticity, NAD+ infusions accelerate mitochondrial recovery, reduce oxidative stress, and support the formation of new neural connections. Patients consistently report improved energy, mental clarity, and reduced cravings when NAD+ is included in the protocol.

Our facility maintains emergency resuscitation equipment including defibrillator, advanced airway management, and cardiac medications on-site at all times. The attending physician holds advanced cardiac life support certification. Cozumel General Hospital is 8 minutes from our location, and we maintain a standing transfer agreement for any situation requiring hospital-level intervention. In over 900 treatments, we have maintained a zero serious complication record.

Most medications require adjustment or temporary discontinuation before ibogaine treatment due to potential interactions. During pre-screening, our medical director reviews every medication you take and provides a personalized tapering or bridging plan. SSRIs, benzodiazepines, and opioid agonists each require specific protocols. We never ask a patient to stop any medication without physician-supervised guidance and a safe timeline.

Compare Your Options

How Does Ibogaine Compare to Other Treatments?

Ibogaine vs MethadoneIbogaine vs SuboxoneIbogaine vs KratomIbogaine vs NaltrexoneIbogaine vs AyahuascaIbogaine TA vs HCl
Treatment Resources

Explore Our Clinical Resources

Safety Protocols & ScreeningSuccess Rates & OutcomesTreatment Duration GuideCost & Pricing GuideIntegration & Aftercare
Addiction-Specific Protocols

Specialized Treatment Programs

Fentanyl & Synthetic OpioidsOpioid AddictionMethamphetamine AddictionBenzodiazepine SafetyPoly-Substance UseMAT TransitionAlcohol & CocaineContraindications & Safety
Find Treatment Near You

Ibogaine Treatment by State

MindScape Retreat treats patients from every US state. Direct flights from most major cities to Cozumel. Browse all state pages or select your state below.

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Begin Your Transformation

Your moment to heal is now. Don't hesitate.

Contact us today for a no-obligation consultation. Our clinical team will answer every question and guide you through the screening process with compassion and expertise.

Contact Us Today

Evidence & Research

Explore the clinical evidence behind ibogaine therapy

Ibogaine Research HubNEW

150+ peer-reviewed studies, active clinical trials, and emerging evidence — curated by our medical team.

Clinical Trials 2026NEW

Every active ibogaine trial tracked: Stanford MISTIC, DemeRx FDA pathway, UTHealth $50M IMPACT, and more.

Safety Guide

Zero complications in 900+ treatments. Comprehensive cardiac screening and continuous monitoring protocols.

Success Rates

Clinical outcomes from 900+ patients: opioid addiction, PTSD, depression, and neurological conditions.

Latest Research & News

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