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opiod addiction treatment with ibogaine in cozumel mexico near cancun

Opioid Addiction Treatment

Ibogaine Treatment Clinic's pioneering framework for psychedelic-assisted therapy boasts an impressive 98% success rate in alleviating symptoms for individuals grappling with issues such as Opioid addictions. Embark on a profound journey of transformation, unlock fresh perspectives on life, and cultivate the art of mindful living at our clinic on the tranquil Cozumel Island, nestled far from the hustle and bustle of Cancun and Tulum.

Transforming Opioid Addiction with Ibogaine Therapy


Understanding Opioid Addiction

Opioid addiction, encompassing both prescription painkillers and illicit substances like heroin, is a profound public health crisis. We treat all forms of opioid addiction, including dependence on fentanyl, oxycodone, Percocet, and other synthetic opioids. These substances work by binding to specific receptors in the brain to reduce pain but can also produce feelings of euphoria, leading to their high potential for abuse and dependence. Long-term opioid use alters brain chemistry, making it incredibly challenging to overcome without intervention.

The Challenges of Traditional Treatments

Traditional treatments for opioid addiction, such as Methadone and Suboxone, are designed to manage withdrawal symptoms and reduce cravings. However, these maintenance therapies often lead to long-term dependency and do not address the root causes of addiction. Additionally, they come with various side effects and the risk of continued addiction, leaving many seeking a more comprehensive solution.

The Promise of Ibogaine

Ibogaine, a naturally occurring psychoactive substance derived from the root bark of the African Iboga plant, offers a revolutionary approach to treating opioid addiction. Unlike traditional therapies, Ibogaine targets the root causes of addiction, facilitating profound healing and transformation.


How Ibogaine Works

Resetting Neurochemical Balance

Ibogaine’s primary action in treating opioid addiction involves resetting the brain’s neurochemical balance. It interacts with the brain’s opioid receptors to significantly reduce cravings and withdrawal symptoms. By effectively resetting these receptors, Ibogaine helps break the cycle of dependence, providing a pathway to recovery.

Noribogaine: Sustained Healing for Opioid Addiction

A crucial component of Ibogaine’s effectiveness is its metabolite, noribogaine. After the initial Ibogaine treatment, noribogaine remains in the body for several months, continuing to work on the brain’s neurochemistry. Noribogaine binds to the same receptors as opioids but without producing the euphoric effects, helping to prevent cravings and withdrawal symptoms. This extended action helps to maintain neurochemical stability and support long-term sobriety.

Scientific Backing

Research has shown that noribogaine’s interaction with the brain’s opioid receptors is fundamental to its effectiveness in treating opioid addiction. Noribogaine acts on the mu-opioid receptor, the serotonin transporter, and the kappa-opioid receptor, among others. These interactions are believed to help manage withdrawal symptoms, reduce cravings, and stabilize mood.

  1. Mu-Opioid Receptor: Noribogaine binds to this receptor, which is also the primary target of opioids. However, unlike opioids, noribogaine does not produce significant euphoric effects. This helps in reducing cravings and withdrawal symptoms, facilitating a smoother detoxification process.

  2. Serotonin Transporter: Noribogaine inhibits the reuptake of serotonin, which can lead to increased levels of this neurotransmitter in the brain. Elevated serotonin levels are associated with improved mood and reduced symptoms of depression and anxiety, which are common during opioid withdrawal and recovery.

  3. Kappa-Opioid Receptor: By modulating this receptor, noribogaine can help in reducing stress and anxiety, which are often heightened during withdrawal periods. This modulation also helps to alleviate dysphoria associated with opioid dependence.


Long-Term Benefits

The extended presence of noribogaine in the body ensures a sustained therapeutic effect. This prolonged action helps in maintaining neurochemical stability, which is essential for long-term recovery from opioid addiction. Individuals recovering from opioid addiction often face persistent cravings and psychological challenges. Noribogaine’s prolonged effects can support long-term sobriety by reducing these cravings and improving overall mental health.


  • "Ibogaine and Noribogaine: Differences in Their Mechanisms of Action," Frontiers in Pharmacology.

  • "Noribogaine’s Role in Treating Addiction and Neuropsychiatric Disorders," Journal of Psychopharmacology.

  • "Therapeutic Potential of Noribogaine in Opioid Addiction," Neuropharmacology Reviews.

Promoting Neuroplasticity with GDNF

One of the key mechanisms through which Ibogaine exerts its effects is the upregulation of Glial Cell Line-Derived Neurotrophic Factor (GDNF). GDNF supports the survival and growth of neurons, enhancing the brain’s ability to reorganize and repair itself. This neuroplastic effect is crucial for healing the damage caused by long-term opioid use, fostering long-term recovery and mental clarity.


Delving into Underlying Issues

Ibogaine is unique in its ability to facilitate deep psychological insights. During Ibogaine therapy, individuals often experience introspective visions that help them uncover and process underlying emotional and psychological issues contributing to their addiction. This profound inner work is essential for achieving lasting recovery, as it addresses the root causes rather than just the symptoms of addiction.

Specialized Treatment at MindScape Retreat

At MindScape Retreat, we offer specialized Ibogaine therapy programs tailored to individuals struggling with opioid addiction. Our approach is holistic, encompassing pre-treatment preparation, personalized Ibogaine dosing, and post-treatment integration. Our experienced team provides comprehensive support to ensure a safe and effective healing journey.

Pre-Treatment Preparation

Before undergoing Ibogaine therapy, guests participate in thorough preparation, including medical evaluations, psychological assessments, and personalized treatment planning. This preparation ensures that each individual is physically and mentally ready for the Ibogaine experience.

Personalized Ibogaine Dosing

Our medical professionals administer personalized Ibogaine doses, carefully calibrated to each guest’s needs. Throughout the treatment, guests receive continuous monitoring and support to ensure safety and maximize therapeutic benefits.

Microdose and Macrodose Programs

MindScape Retreat offers both a 7-day microdose program and a macrodose option. Each case is meticulously analyzed by our team of doctors and psychologists to determine the most appropriate treatment plan. Microdosing involves administering small, sub-perceptual doses of Ibogaine over a period of days, allowing for gradual healing and integration. Macrodosing, on the other hand, involves a single, larger dose designed to facilitate deep and immediate psychological and neurochemical reset. Our experts decide which approach is right for you based on your unique needs and circumstances.


Comprehensive Intake Process

Upon arrival at MindScape Retreat, each guest undergoes a comprehensive intake process to ensure their safety and suitability for Ibogaine therapy. This process includes:

  • Electrocardiogram (EKG): To assess heart health and ensure there are no underlying cardiac issues.

  • Complete Bloodwork: To evaluate overall health and identify any potential contraindications.

  • Liver Panel: To check liver function, as the liver plays a crucial role in metabolizing Ibogaine.

This thorough evaluation allows our medical team to create a personalized and safe treatment plan for each guest.


Post-Treatment Integration

Following Ibogaine therapy, our team provides extensive integration support, helping guests process their experiences and apply insights gained during treatment to their daily lives. This integration phase is crucial for sustaining long-term recovery and personal growth.


Scientific Evidence and Success Stories

Numerous studies and anecdotal reports highlight Ibogaine’s effectiveness in treating opioid addiction. Research indicates that Ibogaine can significantly reduce cravings and withdrawal symptoms, promoting sustained abstinence. Many individuals who have undergone Ibogaine therapy report transformative experiences, gaining insights into their addictive behaviors and finding a path to healing and recovery.

The Future of Addiction Treatment

Ibogaine represents a groundbreaking shift in addiction treatment, offering hope to those struggling with opioid dependence. By addressing the root causes of addiction and promoting lasting neurochemical balance, Ibogaine paves the way for true healing and a life free from the constraints of substance dependence.



Ibogaine’s unique ability to reset neurochemical balance, promote neuroplasticity through GDNF upregulation, and facilitate deep psychological insights makes it a powerful tool for overcoming opioid addiction. At MindScape Retreat, we are committed to providing safe, effective, and compassionate Ibogaine therapy, empowering our guests to break free from addiction and reclaim their lives.

Choosing Ibogaine therapy at MindScape Retreat is a courageous step towards a brighter, healthier future. Our specialized treatment programs, whether microdose or macrodose, are designed to support you in overcoming opioid addiction, helping you achieve lasting recovery and a renewed sense of well-being. Our comprehensive intake process, including EKG, complete bloodwork, and liver panel, ensures your safety and prepares you for a transformative healing experience. Our team of doctors and psychologists will work with you to determine the best approach for your unique needs, ensuring a personalized and effective healing journey.


Where will your journey begin?

Ibogaine Treatment 

Ibogaine-assisted therapy at our all-inclusive retreat, staffed with certified doctors, nurses, and US practitioners specializing in Iboga treatments. Situated in Cozumel, renowned as Mexico's safest and most stunning locale, our retreat offers an idyllic backdrop for profound healing and exploration. Includes Psilocybin & 5-MeO-DMT. An all-inclusive experience with every stay

Starting at $7,500

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Psilocybin-Assisted Therapy

Experience our 5-day, 4-night psilocybin-assisted therapy retreat, custom-tailored for your unique mental journey. We provide the perfect setting and itinerary for profound exploration and healing. At our retreat, every stay is an all-inclusive experience, featuring snorkeling tours to El Cielo, relaxing beach breaks, cenote visits, and daily explorations across the enchanting Cozumel Island

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5-MeO-DMT (Bufo Alvarius)

Embark on the transformative 5-MeO-DMT journey ("The God Molecule"), a path chosen by many for personal and spiritual growth. This profound experience can significantly enhance your wellness and propel you towards greater mindfulness. At our retreat, we provide diverse options to help you take the next step towards a better, more enlightened self 

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MindScape Retreat Gallery

Our Guests Open
Their Hearts  

"My experience at MindScape Retreat was nothing short of amazing, leading to remarkable personal growth. The doctors and staff were incredibly caring, creating an environment of healing and support."


After my ibogaine treatment at MindScape Retreat, my life has transformed incredibly. Nestled in the serene beauty of Cozumel, the retreat's ambiance is simply delightful, a stark contrast to the bustling Cancún.


Really can’t say enough about how great the experience was and highly recommend them! Went to a clinic before Cancun before and it was more like a hospital. This was a retreat and the attention to detail is great.


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