FDA Breakthrough Therapy
for the Mind & Soul

Medical Screening & Application

Comprehensive intake covering mental health history, current medications (particularly SSRIs, MAOIs, and lithium. all important contraindications), cardiac evaluation, and psychological readiness assessment. We screen carefully and honestly. not every applicant is a suitable candidate.

Preparation Sessions

One to two pre-session meetings with a licensed psychologist. These sessions establish trust, clarify intentions, and teach the foundational skills of navigating a high-dose psilocybin experience: surrender versus control, working with difficult emotions, and breath-anchoring techniques.

Guided Psilocybin Session

A 6 to 8 hour guided session in a carefully prepared environment with eyeshades and curated music. the evidence-based approach used in all major clinical trials. Physician monitoring throughout. A trained facilitator provides continuous presence. The setting in Cozumel allows for optional nature-based ceremony elements post-peak.

Immediate Integration

Integration begins within hours of the session. A debriefing session with your psychologist captures the key themes and insights before they fade. Journaling protocols, somatic practices, and rest support the consolidation of the experience.

Ongoing Integration Support

Structured integration support continues for 30 days post-session: scheduled coaching calls, community connection, and continued access to your psychologist. The session opens the door. integration determines how long it stays open.

Psilocybin mushrooms have a long legal tradition of ceremonial use in Mexico and exist in a permissive legal framework. MindScape operates under medical supervision with full compliance with Mexican medical law. Our physicians and psychologists are licensed professionals conducting structured therapeutic work.

Psilocybin is contraindicated for individuals with a personal or family history of schizophrenia, bipolar disorder type I, or active psychosis. Current use of lithium or MAOIs is an absolute contraindication. SSRIs significantly blunt the effect and require tapering prior to treatment. Our screening process identifies all relevant contraindications.

At therapeutic doses (typically 25mg synthetic or equivalent dried mushroom), most patients report profound alterations in perception, emotion, and sense of self. Visuals are common but secondary. the primary effect is emotional and psychological. Many describe encounters with their deepest fears, highest aspirations, and a felt sense of interconnection. Difficult moments are normal and therapeutically valuable with skilled facilitation.

The clinical evidence consistently shows that set, setting, dose, and therapeutic support are the primary determinants of outcome. not the molecule alone. MindScape provides careful preparation, a controlled therapeutic environment, trained facilitation throughout the session, and structured integration afterward. This framework is what produces clinical-grade outcomes.

The 3-night, 2-session program is $3,500 at Casa Selva (our jungle facility), $5,500 at The Hacienda downtown (from August 10), and $6,500 at the Oceanfront Residence (from August 17). All-inclusive: accommodation, meals, screening, preparation, both guided sessions, and 30-day integration. An optional guided 5-MeO-DMT (Bufo) ceremony adds $1,500. Longer stays are priced by length on your consultation.

Yes. The simplest path is the optional 5-MeO-DMT (Bufo) ceremony add-on ($1,500) on any psilocybin program. For deeper combined protocols with ibogaine and NAD+, our multi-day retreat programs (from $8,500) sequence the medicines carefully under medical supervision.