How it works
Why cocaine is a dopamine problem
Repeated cocaine use floods and then exhausts the brain's dopamine system. Over time the receptors down-regulate, and the result is the hallmark of stimulant addiction: intense craving paired with anhedonia — a flatness where pleasure used to be. Willpower struggles against this because it is a neurochemical deficit, not a character flaw.
Ibogaine modulates dopamine pathways and, through sigma-1 and NMDA receptor activity, appears to support restoration of prefrontal control — the circuitry of impulse regulation. Many people describe a marked reduction in craving after a single session, opening a window we use to rebuild routines, motivation and support.
We say plainly what ibogaine is not: it is not a cure, it is not FDA-approved, and without integration relapse happens. The evidence is promising and growing, and our job is to present it without overstating it.
Safety first
Cardiac screening matters even more for stimulants
Cocaine is cardiotoxic. Long-term use can leave real cardiovascular strain — and ibogaine itself affects heart rhythm. Those two facts together mean screening is not a formality for stimulant patients; it is the gate.
Every patient receives a 12-lead EKG, complete bloodwork and a physician evaluation before we confirm candidacy, and the session runs under continuous cardiac telemetry with physicians present and emergency capability on site. If your heart history or recent use makes treatment unsafe, we will tell you honestly.
The most useful thing you can do is be fully open with the medical team about your use and any cardiac symptoms. That honesty is what lets us keep you safe.
The program
What your treatment includes
Mandatory cardiac screening
12-lead EKG and bloodwork before candidacy is confirmed — essential given cocaine's cardiovascular strain.
Dopamine-pathway focus
The protocol targets the craving and anhedonia that drive stimulant relapse, not just the acute crash.
Supervised session
Continuous cardiac telemetry with physicians present throughout, and emergency capability on site.
Crack and powder
Both act on the same dopamine circuitry; the protocol applies to each, adjusted for use pattern.
90-day integration
Support concentrated in the weeks when reward capacity is still recovering — where stimulant relapse risk is highest.
Co-occurring depression
Anhedonia and depression often overlap in stimulant use; the plan addresses both honestly.
The process
From first contact to integration
Confidential consultation
A free call to understand your use, your health and your goals. No judgment, no pressure.
Medical pre-screen
History, EKG and bloodwork, with particular attention to cardiac health. If it is not safe, we tell you.
The session
Preparation, then the ibogaine session under continuous medical supervision.
Integration
90 days of support as dopamine signaling and reward capacity recover.
Looking for cocaine addiction treatment accessible from your state? MindScape Retreat treats patients from across the US with direct flights to Cozumel. Find ibogaine treatment near you.
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Primary References
Our protocols align with the primary scientific literature, including the MAPS Ibogaine Investigator's Brochure (July 2026), NIDA's psychedelic & dissociative drugs research, and registered trials on ClinicalTrials.gov. Ibogaine remains investigational; we pair published evidence with measured, real-world outcome tracking.
Measured & safe
Recovery you can track. Safety you can trust.
Our proprietary data system measures your progress before, during, and after your stay, and monitors your safety at every step. The same data that keeps you safe is the data that proves it worked.
Validated instruments build your baseline before you travel.
Cardiac and vital monitoring around your session, read in real time.
Your progress re-scored against your baseline, in your portal.
Frequently asked
Cocaine and ibogaine, answered honestly
Alcohol & cocaine treatment · Stimulant case study · Opioid addiction · Financing options