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Planned

Texas IMPACT: State-directed Ibogaine Clinical-trial Program

Sponsor: UTHealth Houston, selected by Texas Health and Human Services Commission as lead institution

Study record at a glance

Design, population, outcomes, and follow-up
Study IDtexas-impact
DesignPlanned state-directed ibogaine drug-development clinical trials; final protocol and implementation details remain in development
Condition / topicAddiction, traumatic brain injury, and behavioral health
PopulationThe broader program description covers addiction, traumatic brain injury, and behavioral health; the cited HHSC page does not define an enrolled population
Sample sizeNot announced on the cited HHSC program page
ComparatorNot announced on the cited HHSC program page
Follow-upNot announced on the cited HHSC program page
Outcome focusProgram-level development of controlled ibogaine research; no study-specific registered outcome set is identified in the cited program source

What it suggests

Texas has selected UTHealth Houston to lead implementation of Senate Bill 2308 and is developing the institutional path for future ibogaine clinical trials

What it cannot establish

A funded or planned program cannot establish safety or efficacy. The HHSC page does not establish a final protocol, enrollment size, comparator, follow-up, or outcomes, and says contract development and requirement issues remain

Recruitment relevance

Enrollment has not opened. HHSC directs interested people to check its program page for later updates and contact information after trials are approved

Do not travel, discontinue medication, or change care based on this summary. The sponsor and the current primary source govern participation decisions.

How this summary was framed

This record reports the design and registered or officially announced research question before interpretation. Unknown sample, comparator, follow-up, and outcome details remain marked as unknown. The Atlas does not infer results from recruitment status, regulatory acceptance, funding, or study completion.

UC Irvine MIND-OUD

Changes in reward-circuit functional connectivity, drug-cue BOLD activation, regional glutamate and glutamine, EEG alpha power, opioid withdrawal, and craving

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DemeRx DMX-1001

Clinical development of DMX-1001, an oral noribogaine candidate, for alcohol use disorder; no registered outcome set is cited in the announcement

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Stanford MISTIC

Change in WHODAS 2.0 disability and functioning scores; the broader editorial record also describes clinical and neuroimaging assessments

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ICEERS Spanish trial

Rate of methadone dose decrease, adverse events at different doses, and electrocardiogram measures including QT interval and ST wave

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The Evidence Atlas is an educational editorial index, not medical advice or a recruitment service. Eligibility and openings must be confirmed with the study sponsor. MindScape Retreat is not a site for these studies.